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Oxidative Stress

Studies and Research Papers

Oxidative 1
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Astaxanthin in Cardiovascular Health and Disease

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Astaxanthin and derivatives have been documented to have cardiovascular protective effects after prior administration both orally and intravenously and across several animal species. It also reduces...

02/2012

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Effects of Astaxanthin in Heart Failure Patients with Left Ventricular Systolic Dysfunction

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Exercise capacity of heart failure patients with the left ventricular systolic dysfunction can be improved by 3 month astaxanthin supplementation...

09/2016

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Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans

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Astaxanthin modulates immune response, inhibits cancer cell growth, reduces bacterial load and gastric inflammation, and protects against...

03/2010

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Dietary astaxanthin enhances immune response in dogs

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Plasma concentrations of C reactive protein were lower in astaxanthin-fed dogs. Therefore, dietary astaxanthin heightened cell-mediated and humoral immune response and reduced DNA damage and inflamm...

04/2011

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Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction

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The results revealed that ASX treatment effectively ameliorated UUO-induced renal injury and dysfunction, inhibited renal fibrosis...

02/2019

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Astaxanthin Promotes Nrf2/ARE Signaling to Alleviate Renal Fibronectin and Collagen IV Accumulation in Diabetic Rats

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AST increased the nuclear content of Nrf2 and HO-1 and SOD1 protein expression and decreased the accumulation of FN and Col IV...

03/2018

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Oxidative 2
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Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction

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ASX alleviates UUO-induced renal injury in mice Histopathological changes in the kidneys were determined by PAS staining. As...

02/2019

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Impact of Astaxanthin on Diabetes Pathogenesis and Chronic Complications

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The literature reviewed here clearly suggests a promising utilization of ASX in diabetes healthcare. ASX is a safe drug with pleiotropic effects and without crucial adverse effects. The...

07/2020

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The Protective Effects of Astaxanthin on the OVA-Induced Asthma Mice Model

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In conclusion, all of the data in this experiment indicated that astaxanthin has a protective effect against OVA-induced allergic asthma mice. The exposure of the mice to astaxanthin...

11/2017

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Astaxanthin, Allergies & Skin​

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In summary, for those individuals with problems of metabolic syndrome, diabetes, hypertension, elevated cholesterol, atherosclerosis and prostate cancer or elevated PSA, I think it is prudent to add astaxanthin as a safe and potentially great health...

07/2011

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Astasanthin Proved Effective in Improving Chronic Obstructive Pulmonary Disease (COPD)

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This study shows that astaxanthin increases antioxidant capacity in lung tissue and prevents emphysema. Astaxanthin is attracting attention as a new candidate substance for COPD...

12/2019

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Blood pressure-lowering effect of astaxanthin may help fight type 2 diabetes: Iran RCT

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Astaxanthin supplementation may benefit type 2 diabetics by lowering their blood pressure and enhancing their glucose metabolism, say researchers in Iran...

03/2018

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High Dose Astaxanthin Lowers Blood Pressure and Increases Insulin Sensitivity in Rats: Are These Effects Interdependent?

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In conclusion, astaxanthin was able to affect both the renin-angiotensin, nitric oxide and glucose-insulin systems at relatively high doses. This... 

02/2011

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Astaxanthin helps improve dysglycemia and blood pressure in patients with diabetes

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New research just published demonstrated that astaxanthin suppl-

ementation improves glucose metabolism and decreases blood pressure in patients with type 2...

02/2018

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Astaxanthin – Powerful Antioxidant – Raises Good Cholesterol and Lowers Triglycerides

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The results show that 12 to 18 mg doses per day significantly reduced triglyceride levels while 6 to 12 mg doses raised good cholesterol.  This ..

01/2016

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Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer’s Disease in APP/PS1 Double-Transgenic Mice

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The findings suggested that AST-DHA attenuated cognitive disorders by reducing pathological features in...

04/2018

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Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer’s Disease-Related Pathological Progression in the Hippocampus of AppNL-G-F/NL-G-F Mice

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The present results indicated that astaxanthin decreased Aβ42...

03/2020

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Astaxanthin is neuroprotective in an aged mouse model of Parkinson’s disease

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In conclusion, we have corroborated our previous findings that AXT is neuroprotective against MPTP induced neurotoxicity in young animals. We show that AXT preserves TH in the striatum and substantia...

02/2018

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Astaxanthin Attenuates Neurotoxicity in a Mouse Model of Parkinson’s disease

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IBA-1 in the SN and striatum of AXT treated mice. Taken together, these studies suggest that AXT has neuroprotective property in the CNS against MPTP neurodegeneration...

02/2017

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Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes

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These results suggest that astaxanthin supplementation results in improved erythrocyte antioxidant status and decreased PLOOH levels, which may contribute to the prevention of dem...

01/2011

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On the Neuroprotective Role of Astaxanthin: New Perspectives?

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These researchers demonstrated that astaxanthin improved learning and decreased memory impairment and neuronal damage. Astaxanthin treatment increased the number of pyramidal neurons of the hippocam...

07/2018

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Effect of Astaxanthin on Cataract Formation Induced by Glucocorticoids in the Chick Embryo

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Higher levels of AST prevented loss of reduced glutathione from the lens. These findings support that AST protects glucocorticoid-induced...

06/2014

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Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights

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There is a growing body of evidence suggesting the beneficial pleiotropic effects of astaxanthin in the prevention and treatment of several..

05/2020

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Astaxanthin Mediates Inflammation Biomarkers Associated with Arthritis in Human Chondrosarcoma Cells Induced with Interleukin-1β

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In conclusion, astaxanthin accumulates in SW-1353 human chondrosarcoma cells and incubatio... 

01/2013

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The P0wer of Astaxantin​

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Astaxanthin may improve the skin condition of both men and women, those with inflammatory skin problems, pigmentation or just aging skin. Natural, food-sourced astaxanthin is best and the form that has been tested and approved by the...

01/2020

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Cosmetic benefits of astaxanthin on humans subjects*

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In conclusion these results may suggest that astaxanthin derived from H. pluvialis can improve skin condition in all layers such as corneocyte layer, epidermis, basal layer and dermis by

combining both oral supplementatio...

01/2012

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Astaxanthin from Haematococcus pluvialis Prevents Oxidative Stress on Human Endothelial Cells without Toxicity

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Astaxanthin has been demonstrated here to inhibit intracellular induced stress in human endothelial cells without any cytotoxicity and...

05/2015

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Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans

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Overall, this study shows that dietary astaxanthin enhanced immune response, and decreased a DNA oxidative damage biomarker and ...

03/2010

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Oxidative Stress Regulation on Endothelial Cells by Hydrophilic Astaxanthin Complex: Chemical, Biological, and Molecular Antioxidant Activity Evaluation

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The use of carotenoids like antioxidants can assist the natural mechanisms of cells in neutralizing ...

09/2017

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Astaxanthin Attenuates Homocysteine-Induced Cardiotoxicity in Vitro and in Vivo by Inhibiting Mitochondrial Dysfunction and Oxidative Damage

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Taken together, our results demonstrated that ATX suppressed...

12/2017

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Astaxanthin Prevented Oxidative Stress in Heart and Kidneys of Isoproterenol-Administered Aged Rats

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The protective effect of astaxanthin was associated with reduction of free radicals by improving antioxidant enzyme function, as well as ...

05/2017

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Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema through Nrf2 Activation in Mice

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Therapy with astaxanthin directed toward activating the Nrf2 pathway has the potential to be a novel preventive and therapeutic strategy for COPD...

11/2019

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